E-mail: secretary@worlddentalconference.com | USA : +1-646-828-7579, UK : +44-203-695-1242 | August 24-25, 2017, Barcelona, Spain  


Diagnosis and Prevention of Oral Disease, Endodontics & Implant Dentistry

Session Introduction

Curd Bollen
Parimplant Research Group, The Netherlands
Title: Implants & Halitosis: screws with a smell

Biography: will be updated soon...

Abstract: Halitosis is still a large taboo in our society, although it is a common problem that affects nearly 25% of the total population. The oral cavity (in particular the tongue dorsum) is the major origin of this “disease” (85%), followed by the ENT-area (10%) and several blood-born diseases (5%) (e.g. diabetes). First the origin of the phenomenon will be discussed. It is explained that volatile sulphur components (e.g. H2S) and amines (e.g. cadaverine), produced by the anaerobic microflora in the oral cavity, are the main contributing fragrances of bad breath. Furthermore the different detection methods (subjective – organoletipcal / objective – Halimeter® and Oral Chroma®) will be highlighted. Although gingivitis, periodontitis and mainly tongue coating are the principle oral causes, also dental implants can strongly contribute to breath odor problems. So furthermore, the origin of breath malodor due to implant-involved causes (e.g. peri-implantitis – microbial leakage - dentures) will be presented. Finally the treatment approaches for all the different origins of implant-halitosis will be proposed and discussed in more detail.

Sarah Qadeer
Thammasat University, Thailand
Title: Digital Diagnostics for Temporomandibular Joint Disorders and Occlusion

Biography: Will be Updated Soon...

Abstract: Technological advancement in the field of clinical dentistry gave way to more accurate diagnostic aids to explore and analyze the Stomatognathic system. While T-Scan Digital Occlusal Analysis Technology can help the clinician to accurately explore the occlusal discrepancies, excessive contact location in the arch and provide tooth contact time and force data, JVA or Joint Vibration Analysis explains the movement of the condyle as it simultaneously rotates and translates down the articular eminence during mandibular movement and the ElectroMyography (EMG) evaluates the movement of the Masticatory muscles at rest and during function. The measurable capacity of T-Scan III™ (Tekscan Inc, Boston, USA), provides force and time irregularities, premature contacts, occlusion time, disocclusion time, force distribution, bilateral simultaneity and frictional contacts in the arch. This measurable occlusal data enhances the clinician’s ability to make precisely targeted adjustments during occlusal equilibration following prosthetic, restorative, orthodontic or implant procedures. Joint Vibration Analysis or JVA™ (BioResearch Inc. Milwaukee, USA), enables the clinician in accurately diagnosing the Temporomandibular Joint Disorders by recording the vibrations as the condyle rotates and translates against the articular eminence and transforms the numeric measurements of the vibrations produced in the TMJ into an indication of the pathology that could be the cause of the signature vibration produced due different pathologies. ElectroMyoGraphy or EMG™ (BioResearch Inc. Milwaukee, USA, records the level of muscle activity at rest and during movements of the mandible. It helps in diagnosing the muscular dysfunction by providing the clinician with measurable data of the patient clenching, grinding and excessive muscle hyperactivity. EMG shows symmetry, synergy and force of muscle activity during functions. Digital Diagnostics Aids such as T-Scan Occlusal Analysis, Joint Vibration Analysis and ElectroMyoGraphy have revolutionized the way dentistry is practiced by providing the clinicians with objective, quantifiable, visual data for better treatment planning and clinical outcome

Qassim University, Saudi Arabia
Title: Various strategies to increase anesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A Systematic Review

Biography: Will be Updated Soon...

Abstract: Patients presented with symptomatic irreversible pulpitis in mandibular posterior teeth can be a challenge for clinician when it comes to pain control. Inferior alveolar nerve block, though is a standard method used universally, is not always successful to produce profound anesthesia. Research has shown that mandibular teeth with symptomatic irreversible pulpitis are difficult to anesthetize than teeth with normal and healthy pulp (1). Failure to achieve anesthesia is more common with inferior alveolar nerve block than other nerve blocks (2). Lidocaine is most commonly used anesthetic agent. It is an amide with short onset of action and produces an intermediate duration of anesthesia when used with adrenaline (3). There are many strategies used to increase efficacy of the local anesthesia. 2.0 Objective To investigate various strategies that may affect anesthetic efficacy of inferior alveolar nerve block local anesthesia (lidocaine with adrenaline) in patients with symptomatic irreversible pulpitis. 3.0 Review Question PICO has been framed as below. Population Intervention Comparison Outcome Patients with symptomatic irreversible pulpitis in mandibular posterior teeth Strategies affecting the efficacy of local anesthesia Inferior alveolar nerve block with lidocaine and adrenaline Effects on anesthetic efficacy 4.0 Evidence gathering and study selection See Appendix C 4.1 Evidence gathering The evidence gathering approach will have four components: 4.1.1 searching databases The data bases in the table below will be searched with a pre-determined strategy as detailed in Appendix A. In cases where search results are small in number, search terms will be reduced to maximize the search sensitivity. Topic/Field Databases Health PUBMED/ MEDLINE Health EMBASE Health SCOPUS Health OVID 4.1.2 The following journals will be hand-searched for relevant articles: Resources that will be searched by hand Journal of Endodontics International journal of Endodontics Australian endodontic journal 4.1.3 Expert network consultations A network of health professional education will be consulted by email to identify additional grey literature or research that has not been found through the above processes. 4.1.4 Reference searches Bibliography of those papers that match the eligibility criteria below will be searched by hand to identify any further, relevant references, which will be subjected to the same screening and selection process. 4.2 Eligibility criteria After gathering the evidence, the following eligibility criteria will be applied to the results and all identified references screened independently by two reviewers using a three-stage approach to reviewing the title, abstract and full text. 4.2.1: Types of studies: Only randomized clinical trials will be included in this review. 4.2.2: Types of participants: This review will include patients with symptomatic irreversible pulpitis in mandibular posterior teeth. 4.2.3: Type of intervention Strategies like premedication, use of supplemental anesthesia that may affect the anesthetic efficacy of inferior alveolar nerve block with lidocaine, will be reviewed. 4.3.3: Type of outcome measures: Primary outcome of interest is to evaluate the factors that can affect the efficacy of inferior alveolar nerve block. 4.3: Exclusion Criteria Editorials, newspaper articles and other forms of popular media will be excluded. Failure to meet any one of the above eligibility criteria (section 4.2) will result in exclusion from the review and any apparent discrepancies during the selection process will be resolved by a third, independent reviewer. The number of excluded studies (including reasons for exclusion for those excluded following review of the full text) will be recorded at each stage. 5.0 Assessment of risk of bias and data extraction Data will be extracted from relevant papers. Data will be collected regarding the reasons for exclusion. 6.0 Data synthesis The availability of appropriate data and resources to conduct a meta-analysis will be considered, where feasible. 7.0 Dissemination A final set of tables including a GRADE Evidence Table and Descriptive Evidence Table will be produced.

Dana G Colson
University of Toronto, Canda
Title: Impact of Dentistry on Mental Illness

Biography: Dr. Dana Colson is a true pioneer in dentistry. She has a wellness-based dentistry, leading edge practice in Toronto that has been mercury free for the past 33 years. Dr. Colson has fully integrated technology, including lasers, digital radiography and drill-less dentistry, while maintaining a preventative and holistic philosophy. Dr. Colson is author of Your Mouth: Gateway to a Healthier You, relief aid worker and popular speaker. She recently did a two week give back with the Maasai in Kenya. Dr Dana Colson teaches internationally and is a mentor at the Kois Center. She is an accredited member with the International Academy of Oral Medicine and Toxicology. She recently completing a global MBA. Her wellness based practice is based on minimally invasive dentistry with leading edge technology.

Abstract: "Impact of Dentistry on Mental Illness" from the perspective of how various dental materials, teeth alignment and arch formation , grinding and clenching, and sleep apnea all contribute to one's wellbeing. Observations and solutions are presented from a clinical perspective.

John J Dzakovich
Title: The Mysterious Noncarious Cervical Lesion

Biography: Will update soon..

Abstract: 1. The Mysterious Noncarious Cervical 2. John J. Dzakovich, D.D.S., M.A.G.D., A.C.D. 3. John J. Dzakovich, D.D.S., M.A.G.D., A.C.D. 4. In 1907, W.D. Miller, D.D.S., M.D., PhD.,ScD, published the results of his extensive research, which determined the etiology of non-carious cervical lesions (NCCL). Because all subsequent attempts to reproduce the non-carious cervical lesion failed and the literature reveals only hypothetical opinions, current-day beliefs suggest a multifactorial etiology. The purpose of this study was to compare the effects of modern-day materials (toothbrushes and toothpastes) on hard tooth structure to those used by W.D. Miller 100 years ago. Based on the presenter’s 20-year in vitro studies, the research and his own clinical observations, the true etiology will become apparent. 5. Attendees will learn: • A)A historical review illuminating the development of the hypothetical multifactorial etiology of the non-carious cervical lesion. B) The etiology of the NCCL via in vitro studies (100 years ago and today). C) A better understanding of oral hygiene/oral harm. D) The primary etiology of the noncarious cervical lesion. E) The primary etiology of incisal/Occlusal cupping and cratering. F)The actual role occlusion plays in the formation of these lesions. G) The role of acid in the formation of these lesions. H) Developingappropriate treatments plan to prevent and restore these lesions. 7. Dr. Dzakovich has been in private practice his entire professional career and mentored a dental study club for 10 years. He has completed and published three in vitro studies regarding the effects of toothpaste and toothbrush on the human dentition. After verifying Dr. W.D. Miller’s research, he conducted two studies showing the effects of toothpaste and acid on incisal/occlusal cupping/cratering of teeth. He is currently conducting an in vitro study regarding the effects of acid-challenge on the noncarious cervical lesion.

Mostafa Ahmed Anwar Salama
The British University Egypt
Title: The Art of Single File For Root Canal Treatment & Retreatment

Biography: I am an Assistant Lecturer of Endodontics at the Faculty of Dentistry, The British University in Egypt & Infection Control Officer at the British University Dental Hospital. I am a Certified Healthcare & Hospital Management Specialist – AUC. I took a Master Degree of Endodontics from Ain Shams University in Egypt, June 2015. My practice is limited to Micro-Endodontics. I am a Lecturer & Participant in many International Dental Conferences. I conduct many Lectures and Hands-on workshops on Endodontics all over Egypt. I am an Endodontics Specialist at Whity Dental Center, Cairo (Egypt).

Abstract: In this study OneShape file (OS) was compared to R-endo file (RE) in retreatment of endodontically treated teeth in terms of time required for completion of retreatment procedure and amount of remaining gutta-percha on root canal dentin. Methods: Sixty mandibular mesio-buccal canals with angles of curvature between 15 and 45 degrees were prepared using Protaper Universal rotary files then obturated using gutta-percha and AH-plus sealer. Canals were then divided equally into 2 groups according to the retreatment system. Time required to reach the full working length and for complete removal of gutta-percha were measured during retreatment procedure using a digital stopwatch. Also the amount of remaining gutta-percha on the root canal dentin was measured using Stereomicroscopic images analyzed by Image J software. Results: OS group recorded statistically significant less time required for retreatment and less amount of remaining gutta-percha than RE group. Conclusion: OS system showed less time required for retreatment and less amount of remaining gutta-percha on the root canal dentin when compared and analyzed by Image J software.

Anurag Tripathi
King George’s Medical University, India
Title: Estimation & co-relation of Salivary Amylase and Pain Levels in Myofascial Pain dysfunction Syndrome

Biography: Dr. Anurag Tripathi M.D.S.in Oral Medicine and Radiology (June 2006) from Sri Ramachandra Deemed University, Chennai, Tamil Nadu. Presently working as Associate Professor in the Department of Oral Medicine and Radiology, Faculty of Dental Sciences, King George Medical University since 2007, having 10 years of academic and research experience. Presently involved in undergraduate teaching and Guide of MDS students. Having intra-mural and extra-mural research projects and multiple publications. Member of various national and international professional bodies in the field of oral medicine and maxillofacial radiology. Was elected executive committee member of Indian academy of oral medicine and radiology for the year 2014.

Abstract: The present study was planned to evaluate the level of salivary alpha-amylase (sAA) in healthy individuals and Myofacial pain syndrome (MPS) patients and to find the reliability of salivary alpha amylase as a biomarker for pain. After obtaining ethical approval, the salivary sample for estimation of amylase was taken using NAVAZESH method of clinically diagnosed MPS patients (criteria by RDC) (Group I) and age & sex matched control group (Group II). Visual Analog scale (VAS) score for each individual was recorded co-related with salivary amylase. Statistical analysis was done using SPSS software 16.0. The sAA was significantly higher amongst Group I (149.92±21.1) compared to Group II (91.18±5.4). There was significant difference in VAS among different age groups and sex. The salivary alpha amylase levels progressively reduced in patients as the age increased. Group I. However, mild negative correlation was found between VAS and sAA in Group II. To our knowdge,this is the first known study to date, to highlight the sensitivity of sAA as an effective marker in assessment of pain severity in MPDS patients on the basis of VAS scale. The level of salivary alpha-amylase was significantly correlated with the pain severity assessed by VAS.

Rajesh Dashaputra
Bhabha Atomic Research Center Hospital,India
Title: Changing paradigms in Maxillary Sinus management and alveolar Augmentation in modern 3D implant dentistry

Biography: Dr. Rajesh Dashaputra completed his Bachelor of Dentistry (B.D.S.) from University of Mumbai in 1985. He has trained in implantology very early when implants were introduced in India and joined as member of ICOI(International Congress of Oral Implantologists) since 1995. He now has mastered more than 16 systems and mentors for few of the leaders. He also completed PGDM in Clinical Research with specialisation in CDM ( clinical data management). He has been working in prestigious research institution of BARC under the dept. of Atomic Energy, govt. of INDIA for more than 20 years as a busy consultant dental implant surgeon with full use of digital technologies including CT and CAD CAM . He has pioneered in another area of interest - healthcare informatics. He is fully trains students in implantology, healthcare software systems and telemedicine. He also has publications in IJME ( Indian journal of medical Ethics) and involved in stem cell and biomaterials research.

Abstract: Implant dentistry defined the next step beyond routine modalities of salvaging dilapidated dentition with root canals, crowns and bridges. Major focus turned towards full arch rehabilitations on implants but limitations were in negotiating critical anatomic structures like the maxillary sinus, and the inferior alveolar nerve or poor bone anatomy. Modern dentistry with sophistication in 3D diagnostic technologies, evolution in tools for surgical management of bone and newer biomaterials in grafting ranging from bone substitutes, barrier membranes and use of Platelet Rich Plasma and growth factors now yields better bolder and predictable outcomes to rehabilitations which earlier was considered difficult. The talk reviews a full overview and comparative benefits and pit falls of all.

Oral Pathology, Oral Cancer,Therapy and Treatment ,Cell and Tissue Biology &Future Trends in Dentistry

Session Introduction

Mahmoud Abu-Ta’a
Arab American University-Jenin Palestine, Israel
Title: One-stage full-mouth disinfection combined with locally delivered Minocycline: A randomized, single-centered, placebo-controlled trial.

Biography: Dr. Mahmoud Abu-Ta'a is an EFP-Certified periodontist and a full-time associate professor of periodontology; teaching periodontology and dental implantology for graduate and undergraduate students at the Faculty of Dentistry, the Arab American University. Dr. Abu-Ta’a holds a master degree, a specialisation certificate and EFP certificate in periodontology from the Catholic University of Leuven, Belgium. Dr. Abu-Ta’a has published several scientific papers in peer-reviewed journals such as the Journal of Clinical Periodontology and Clinical Oral Investigations. Dr. Abu-Ta’a maintains a private dental office limited to periodontology and dental implantology in Jerusalen, Israel.

Abstract: To compare the clinical benefit of minocycline locally administered immediately after completion of one-stage full-mouth disinfection (OSFMD) in patients with generalized aggressive periodontitis up to 6 months after therapy. MATERIAL AND METHODS: This single-center, placebo-controlled, randomized study included 36 patients. After OSFMD, a test and a control group were selected by means of a computer-generated randomization list. Test group (n=18; 11 females and 7 males) received locally delivered minocycline, in all deep periodontal pockets (PPD > or = 6 mm) and the control group (n=18; 13 females and 5 males) received OSFMD and a placebo. Both groups received thorough oral hygiene instructions. After 3 and 6 months, the clinical periodontal RESULTS: The minocycline group showed a significant (p < 0.05) additional pocket depth reduction and additional clinical attachment gain for pockets of single- and multi-rooted teeth compared with the control group. A significant (p < 0.05) lower percentage of sites with probing pocket depth ≥5 mm were shown for the minocycline group compared with the control group. CONCLUSION: The use of locally delivered minocycline after OSFMD offers an additional clinical improvement in patients with generalized aggressive periodontitis over a 6-month period.

Alessandro Leonida
Milano-Bicocca University, Monza
Title: The modification of the environment as a key to success in bone regenerative therapy

Biography: Alessandro Leonida has a degree in dentistry at the Dental School of Milano Statale University in 1998, he completed his perfection in oral-maxillofacial surgery at te age 29 years from Istituto Stomatologico Italiano. He completed his PhD in Neuroscience at the age of 35 at Milano Bicocca University - School of Medicine and he is a researcher in the same University. He has published many papers in reputed journals and five books. The last book “The stem cells and gene therapy in dentistry” was published in March 2017.

Abstract: Environmental adaptation allowed the evolution and therefore the prosecution of life on Earth. In 2005, Kendall Powell on Nature journal introduced an important concept for both the retrieval and the study and developing of stem cells, in different tissues of our organism: the ECOLOGIC NICHE. Thinking about stem cells in isolation become important, it could be productive thinking about an individual component of a bigger system, more complex; actually it is falsely simplified. Another concept is linked to this one; it was introduced by Blau in 2001, who said that the modification of the environment plays a significant role in the differentiation of multipotent stem cells. The aim of the study is to evaluate the influence of the environmental modification histologically, using inducible solution in bone healing. In this clinical-histological study were selected 6 patients in good health, with an age between 35 to 58, 4 male and 2 female, which needed the extraction of at least 2 teeth. All patients accepted a therapeutic plan, which included the implant placement in order to solve their partially edentulous. In one dental alveolus was placed a heterologous biomaterial (AD bone®) blended with normal saline. In the second alveolus, the biomaterial was blended with inducible solution. After 60 days, during the reopening phase due to a previous implant placement, it was taken a sample with a milling cutter trephine 2mm for histological examination at the Department of Anatomy at Brescia University. The authors tried to demonstrate how there is no need to place more stem cells in a bone loss zone in order to get it better, but an environmental modification is sufficient to improve it.

Nova M. Aghbashia
University of California, USA
Title: Gateway to the Future Laser Dentistry- Facts and Applications

Biography: Doctor of Dental Surgery (D.D.S). School of Dentistry, University of California San Francisco. - Doctorl Research Scholarship. RWTH University Dental School, RWTH Aachen University, Germany. - Master of Science in Conservative Dentistry (M.Sc). College of Dentistry, University of Baghdad, Iraq. - Post-graduate Residency training in Conservative Dentistry. - Bachelor of Science in Oral & Dental Medicine & Surgery (B.D.S). College of Dentistry, University of Baghdad, Iraq. CURRENT AND FORMER POSITION - Lead Dentist - Benevolence Health Center, CA- USA - Private General Dentistry Practice, CA – USA - Former Assistant Professor, Western University - College of Dental Medicine, CA – USA - Visiting Dentist /Researcher, Department of Dental Preservation, RWTH Aachen Dental School, Aachen -Germany. - Former University Lecturer / Researcher, College of Dentistry, University of Baghda - Iraq. LECTURE & PRESENTATION - Introduction to Laser Dentistry – Clinical Facts and Limitation. Western University - College of Dental Medicine, USA - Intra radicular dentin - Laser Interaction Aspects: Summary of Ablation Controlling Factors. USCF Dental Alumni Association 116th Scientific Session. San Francisco, USA. - Laser In Endodontic. - UCSF Dental School. San Francisco, USA. - In Vivo Comparison of Bactericidal Efficiency of Conventional Periodontal Treatment & Periodontal Treatment Assisted by KTP-Laser. USCF Dental Alumni Association 115th Scientific Session. San Francisco, USA. - Intracanal Dentin - Er,Cr:YSGG Laser Interaction Aspects: Summary of Ablation Controlling Factors. UCSF Research and Clinical Excellence Day. San Francisco, USA. - In vitro preliminary study to evaluate the capability of Er,Cr:YSGG laser in posterior teeth root-canal preparation with step-back technique. 16th DGL

Abstract: Understanding the Concept and Reviewing the  Unique Aspects of Clinical Applications      Laser technology has been successfully incorporated in  many fields of modern dentistry during the last decade.   As a new tool in dental practice, laser technology has  positively expanded the scope of attractive, painless  dental procedures and effectively found its way into the  mainstream of dentistry. Yet, its clinical performance and  procedural limitation represent one of the most  controversial topics of recent dental literatures and  conferences discussions.      This presentation will review the scientific concept of  photo‐ablation theory and its application in dental field.  Moreover, it will discuss the laser tools and delivery  modes as well as the safety measures required for using  this technology in different dental setups.    This presentation will also review the use of laser in the  various disciplines of dentistry and discuss which specific  lasers should be used for each of those disciplines.     Finally, the presentation will review criteria that will help  dentists to select the right laser for their practice.      This presentation will achieve the following objectives:  • General overview of the basic concept of laser  application in modern  dentistry   • Demonstrate the biological rationale for the use  of laser in dentistry  • Identify the types of laser‐tissue interaction   • Differentiate available laser wavelengths used  in dentistry and identify the specification of  each wavelength.  • Identify the most important laser applications in  dental practice including the recommended  techniques, advantages, disadvantages and  limitations 

Udeabor Samuel
King Khalid University, Saudi Arabia.
Title: Evaluation of Tumor Associated Macrophages and angiogenesis in ameloblastoma

Biography: Will be Updated soon..

Abstract: Ameloblastoma is a locally invasive odontogenic neoplasm that has a high recurrence rate [1]. The invasion of adjacent tissue is supported by angiogenesis stimulated by tumor-associated macrophages (TAMs) [2]. TAMs are macrophages modified in the milieu of the tumor microenvironment and have very weak or no ability to present antigens. Thus there is collaboration between the tumor and the tumor microenvironment to maintain tumor enlargement. TAMs exist as the classically activated M1 macrophages that possess antitumor activity and the otherwise activated M2 macrophages that support tumor invasion and metastasis [3]. We investigated the relative expression and topography of TAMs and CD34 in ameloblastoma to assess their affiliation and effect on tumor growth. Materials and Methods Forty-six FFPE blocks of ameloblastoma were processed for Abcam Mouse monoclonal Anti-CCR7 antibody, Abcam Rabbit polyclonal Anti-CD206 antibody and Dako Mouse monoclonal Anti-CD34 antibody QBEnd-10.Cytoplasmic/membrane brown staining was taken as positive for all antibodies. The relative percentage of TAMs were classified as: <5%, 5-25%, 25-50% and >50%.TAMs related microvessel density (MVD) was evaluated as the mean of the three-recorded values. Cases with no CD34+ vessels adjacent to the TAMs region had MVD score of 0. Results Macrophages adjacent to peri-tumor islands were marked by CD206 and CCR7 and we noted negligible intra-tumor presence of positive macrophages (Figure 1 & 2). The percentage of positive CCR7 immune cells was greater than that for CD206 in 38 (82.6%) cases, approximately equal to CD206 in 6 (13%) cases, and the CD206 expression was more than CCR7 in only 2 (4.3%) cases. In 34 (73.9%) cases the area of MVD did not overlap with the region of TAMs but in 4 (8.7%) cases (where MVD overlapped TAM1) the average MVD score was 20 (Table 1).

Kermanshah University of Medical Sciences, Iran
Title: Study of apoptosis in oral pemphigus vulgaris using immunohistochemical marker Bax and TUNEL technique.

Biography: DENTIST,ORAL PATHOLOGIST,DDS,Msc. I have published afew articles in well known journals.they can be searched on Google scholar.

Abstract: BACKGROUND: Pemphigus vulgaris (PV) is an autoimmune mucocutaneous disease presenting clinically with blisters or erosions of the skin and mucous membrane. The main histopathologic characteristic of this disease is suprabasal vesicles due to loss of cell-cell adhesion between keratinocytes named acantholysis. Studies have shown that apoptosis is increased in PV. The purpose of this study is to investigate the role of apoptosis in blister formation in PV. METHODS: This cross-sectional study was conducted on 25 specimens of oral PV. The presence of apoptosis was evaluated using the TUNEL technique in the normal perilesional region, vesicle area, and acantholytic cells. Also, the expression of Bax pro-apoptotic marker was assessed by the biotin-streptavidin immunohistochemical method. SPSS software was used for Wilcoxon test analysis. P values <0.05 were considered significant. RESULTS: The percentage and intensity staining of TUNEL-positive cells were noteworthy. There were statistically significant differences between basal and parabasal (P = 0.05), tombstone with vesicle roof (P = 0.038) and basal with tombstone (P = 0.038). However, the expression and staining intensity of pro-apoptotic marker Bax were weak, and no statistically significant differences were observed between the various areas. CONCLUSION: The results obtained in the present study suggest that the process of apoptosis occurs early in PV because it was observed in the perilesional normal appearing tissue. Also, the process of apoptosis may cause exacerbation or speeding of the bulla formation. In other words, inhibition of apoptosis in the patients could reduce the severity of the lesions.

Reem Hanna
Title: The scope of laser therapy in the management of oral mucosal pathology and oral conditions.

Biography: Dr Reem Hanna is a registered Specialist in Surgical Dentistry with the General Dental Council. Dr Hanna has over ten years experience in Oral and Maxillo Facial Surgery. She did her post-graduate masters degree at The Eastman Hospital and has a Diploma in Conscious Sedation from King's College in Camberwell where she is currently an associate specialist.

Abstract: The use of the conventional method in terms of excisional and incisional biopsies of oral mucosal lesions has been the golden standard tool in the diagnosis and treatment of various oral pathologies. Laser technology in the recent years has added a great value in the management of different oral pathology in terms of the less post-operative complications, pain management, reduction of bacterial pathogens, wound healing, reduction of lesion’s severity and incidence and the enhancement of facial aesthetic especially in some vascular lesions. Furthermore, photobiomodulation has demonstrated to be effective in management of neuropathic pain. Aim and objectives of this presentation are: - - To recognize the scientific principles and knowledge underpinning the laser-assisted applications in the management of various oral soft tissue lesions. - An overview of the advantages of laser therapy in comparison to the conventional methods. - To acknowledge the effectiveness of photobiomodulationin reducing neuropathic pain associated with different oral conditions. Conclusion: Laser therapy is a novel concept in treating oral mucosal lesions, reducing neuropathic pain in burning moth syndrome, improving patients’ quality of life.However, further randomized control trail studies and double-blind/placebo-controlled studiesare required to provide more evidence-based practice in the management of various oral pathologies.

Arupratan Choudhury
BIRDEM Hospital Dhaka, Bangladesh
Title: Links between oral & general health – The Mouth-Body Connection

Biography: Arup Ratan Choudhury is the Hon. Senior consultant of BIRDEM Hospital (WHO collaborating Centre) & Professor of Dental Surgery, Ibrahim Medical College (1987-till now). He graduated from Dhaka University & obtained BDS (Bachelor of Dental Surgeon) in 1976 & WHO Fellowship in Dental Public Health from London University in 1983, Research Fellowship from SUNY at Stony Brook, New York, USA in 1993 & PhD (Doctor of philosophy) from Dhaka University in 2001 & FDSRCS (England) from Royal College of Surgeons, London in 2012. He is working in the field of Dental Surgeryfor the last 37 years & presented 39 scientific papers in International seminars. He is also the founder president of MANAS-Association for the Prevention of DrugAbuse & received “Tobacco or Health” Medal in 1998 from WHO for outstanding Contribution in the field of Anti-tobacco Movement in Bangladesh. He has Published 12 books on Dentistry, Tobacco hazards& Drug abuse.

Abstract: Oral conditions have an impact on overall health and disease. Bacteria from the mouth can cause infection in other parts of the body when the immune system has been compromised by disease or medical treatments (e.g., infective endocarditis). Systemic conditions and their treatment are also known to impact on oral health (e.g., reduced saliva flow, altered balance of oral microorganisms). Oral health is essential to general health and well-being at every stage of life. A healthy mouth enables not only nutrition of the physical body, but also enhances social interaction and promotes self-esteem and feelings of well-being. The mouth serves as a “window” to the rest of the body, providing signals of general health disorders. For example, mouth lesions may be the first signs of HIV infection, aphthous ulcers are occasionally a manifestation of Coeliac disease or Crohn’s disease, pale and bleeding gums can be a marker for blood disorders, bone loss in the lower jaw can be an early indicator of skeletal osteoporosis, and changes in tooth appearance can indicate bulimia or anorexia. The presence of many compounds (e.g., alcohol, nicotine, opiates, drugs, hormones, environmental toxins, antibodies) in the body can also be detected in the saliva. Oral disease is the most widespread chronic disease, despite being highly preventable. It has become increasingly clear that the oral cavity can act as the site of origin for dissemination of pathogenic organisms to distant body sites, especially in immunocompromised hosts such as patients suffering from malignancies, diabetes, or rheumatoid arthritis or having corticosteroid or other immunosuppressive treatment. A number of epidemiological studies have suggested that oral infection, especially marginal and apical periodontitis, may be a risk factor for systemic diseases. The oral cavity contains some of the most varied and vast flora in the entire human body and is the main entrance for 2 systems vital to human function and physiology, the gastrointestinal and respiratory systems. Several diseases involve these 2 systems and manifest in the oral cavity. In addition, a specific pathologic condition, such as periodontitis (ie, inflammation of the periodontal attachment of the teeth and the alveolar bone), may be present in the oral cavity. These specific conditions in the oral cavity may create foci of infection that can affect many other vital systems, such as the cardiovascular and renal systems. Foci of infection in the oral cavity arising from chronic periodontitis or chronic periapical abscesses (ie, inflammation and abscess of the tissue attached to the apex of the root) may lead to subacute bacterial endocarditis (BE) and glomerulonephritis (GN). That the mouth and body are integral to each other underscores the importance of the integration of oral health into holistic general health policies and of the adoption of a collaborative “Common Risk Factor Approach” for oral health promotion.

Ranjitkumar Patil
King George’s Medical University,Lucknow-India
Title: Serum malondialdehyde estimation in oral cancer and precancer

Biography: Professor& Head M.D.S. (Oral Diagnosis,Medicine & Radiology) from GDC Nagpur in 1998 Experience -Worked at various institutions like Nagpur, Wardha, Vadodara & Lucknow -Postgraduate Teacher since 2003 -Scientific publications in various National & International Journals -Scientific presentations in various National conferences Reviewer of following Journals 1) Journal of Oral Oncology 2) Journal of Forensic & Legal Medicine 3) Journal of Oral Biology & Craniofacial Research, Elsevier Publication 4) National Journal of Integrated Research in Medicine, Bhavnagar University (Gujrat) 5) Ex Member of Editorial Board of Journal of Oral Medicine & Radiology, (2009-2011) Jaypee Publication

Abstract: Tobacco and alcohol induces generation of free radicals and reactive oxygen species which are responsible for high rate of lipid peroxidation. Malondialdehyde is the most widely used marker of lipid peroxidation. The aim of the study was to estimate serum malondialdehyde level in oral precancer, oral cancer and normal individuals. In this study serum malondialdehyde was measured according to the method of Ohkawa et al in 30 normal individuals and 30 patients each with histopathologically diagnosed oral precancer and oral cancer. The mean serum malondialdehyde level in the control group was found to be 5.107 ± 2.32 ηmol/ml, whereas it was 9.33 ± 4.89 ηmol/ml and 14.34 ± 1.43 ηmol/ml in oral precancer and oral cancer, respectively. There was statistically significant increase in serum malondialdehyde levels in the oral precancer and oral cancer patients compared with the control group. Increased serum malondialdehyde in oral cancer and oral precancer would serve as a valuable marker for both preventive and clinical intervention, and may deserve further investigation for the early diagnosis, treatment, and prognosis.

Akhilanand Chaurasia
King George’s Medical University,Lucknow-INDIA
Title: Mandibular ramus as dimorphic tool in age and sex determination-A cross sectional radio-anthropometric study on digital panoramic radiograph

Biography: Dr.Akhilanand Chaurasia, Associate professor and consultant at King George Medical University,Lucknow has dedicated meticulous efforts and supreme services pertaining to oral medicine and oral biology. Dr. Akhilanand chaurasia has an elite academic record. He is graduated from King George’s Medical University in 2005 and completed his postgraduation from University of Kerala in 2009. He has diploma in Healthcare biomedical waste management. He has remarkable credit of contributing to academics by publishing 54 manuscripts,peer reviewers of more than 150 international journals, editor in cheif of 2 national journals, associate editor of 1 international journal, editor of 10 international journals,editorial board members of 17 international journals, ambassador of European association of cancer research. He is fellow of many prestigious and pristine organizations of dentistry. He is member of 30 international organizations. He is active guide and mentor of postgraduate programmes. Currently he is persueing PhD in chronobiology of Head and Neck cancer.

Abstract: This research article focuses on prediction of age on the basis of maximum ramus breadth, minimum ramus breadth,condylar height, projective height of ramus and coronoid height.(Linear regression analysis).However it also determine sex of individual on the basis of discriminant function analysis using Fischer exact test using maximum ramus breadth, minimum ramus breadth, condylar height, projective height of ramus and coronoid height. Material and Methods: The orthopantomograms of 200 subjects were taken from planmeca promax-dimax4 OPG machine at 66 Kvp, 8mA and exposure time 16 sec. All the measurements are done on digital orthopantomograms using planmeca Romexis 3.2.0R software. The measurements of the mandibular ramus will be subjected to Discriminant function analysis. Results: The study sample consists of 200 subjects aged between 8 to 82 years with a mean age of 38.21±17.12 years. The persons correlation coefficient (r) between age and minimum ramus breadth was not significant correlation however the maximum ramus breadth, condylar height, coronoid height and projective height were directly associated with age and demonstrate a significant positive relation in maximum ramus breadth,condylar height,coronoid height and significant positive relation in projective height. The maximum ramus breadth, min ramus breadth, condylar height, coronoid height and projective height values were greater in males than females. The difference in maximum ramus breadth, minimum ramus breadth, condylar height, coronoid height and projective height values in males and females were statistically significant (P<0.05) Conclusion: Mandibular ramus can be a useful tool for age and sex determination in forensic science.Thus medicolegal cases having age and sex issues can be resolved with measurements of mandibular ramus if panoramic radiograph is available.

Vishnu Dental College, Bhimavaram
Title: Analytical Reasoning in Oral Pathology

Biography: Dr. Govindraj Kumar N, MDS in Oral Pathology is presently Professor and Head of Department of Oral and Maxillofacial Pathology and Microbiology, Vishnu Dental College, Bhimavaram, Andhra Pradesh. He also holds the post of Vice-President of Indian Association of Oral & Maxillofacial Pathologists. He is also a member of the International Association of Oral Pathology. In addition, he is a member in High Power Committee for Medical, Dental and allied sciences, Government of Andhra Pradesh, India. He is a life member for Indian Dental Association and International Association of Dental Research. He is Phd registration committee member for Rajeev Gandhi University of health sciences, Bangolore. He secured his BDS degree from Kuvempu University, Karnataka, India, and attained MDS degree from Dr. MGR Medical University, Chennai. His field of expertise is oral precancer, oral cancer and odontogenic tumors. He received special training in head & neck oncopathology at Kidwai Institute of Oncology, Bangalore, India. He received best paper award for title, "What is new in cancer therapy" at THE Indian dental conference held at Vijayawada IN 2003. He has authored many international and national publications, most of which are indexed in PubMed. He has delivered more than 40 scientific deliberations in various scientific forums as a keynote speaker. He has also been a part of various organizing committees of national and international conferences held in different states of India. He is also part of organizing team for the upcoming international IAOP & IAOMP conference going to be held at Chennai in September 2016. He is also a recognized post graduate examiner for many reputed universities across India.

Abstract: Mouth is the mirror of many systemic diseases. There are many clinical manifestations, which are either common or specific for a particular disease. However, most texts books do not explain the mechanism underlying these manifestations or provide a logical reason. For example, generally skin lesions heal with scaring and whereas oral wounds do not. Similarly, some individuals develop malignant tumors while others develop benign tumors – why this discrimination? Likewise, most books do not elucidate the reason behind names of diseases. For instance, why does one call chicken pox as "chicken" pox? Does it have anything to do anything with chicken? The purpose of this presentation is to analyze and provide valid reasons for various clinical and histopathological manifestations which we come across in the field of oral pathology.

Periodontology, Periodontics, Pediatric Dentistry & Prosthodontics.

Session Introduction

Osmangazi University, Turkey
Title: Inhibition of cathepsin K

Biography: Dr. Beklen received her dental licentiate degree and then continued her master study on biomedical engineering. During her PhD study, Dr. Beklen focused on the host response in periodontal disease and she is a specialist in periodontics.

Abstract: Periodontitis is a complex inflammatory disease destroying tooth supporting tissues with multifactorial aetiology. The underlying pathogenesis is an inflammatory process, which finally causes host-mediated destruction of hard tissue as well. Activation of the bone resorption requires the adhesion of osteoclasts to bone and release of proteases to digest bone matrix proteins. Among these factors, cathepsin K is an enzyme which is predominantly expressed in osteoclasts and is capable of cleaving collagen. Although cathepsin K is specifically expressed in osteoclasts, our study on non-osteoclastic source, namely gingival fibroblasts showed that cathepsin K expression is increased during inflammation in vivo and gingival fibroblast stimulation causes active cathepsin K release invitro. It is now further analyzed if different cathepsin K inhibitors can be used as a therapeutic target on gingival fibroblasts using cell culture, in vitro?

Mahmoud Helmy Belal
Tokyo Medical & Dental University, Egypt
Title: An overview of surgical periodontal therapy. Time and timing procedure in the success rate.

Biography: Prof. Dr. Mahmoud Helmy Mohamed Abd Allah Belal, BDS, MSc (Egypt), PhD (Japan) is a clinical professor & consultant, Oral Medicine, Periodontology, Oral Diagnosis & Radiology Department, Faculty of Oral & Dental Medicine; Damanhour University; Damanhour; Egypt. His work was concentrated on Periodontics & Oral Medicine fields. He finished Bachelor degree (1990), Master degree (1997) from Tanta & Mansura & Universities, Egypt; Ph.D. degree (Nov. 2005) from Tanta University, Egypt as well as from Tokyo Medical & Dental University, Graduate School, Department of Hard Tissue Engineering (Periodontology), Tokyo, Japan (Mar. 2003 ~ Jan. 2005). He worked as lecturer (Nov. 2006 ~ start of 2011), associate professor (2011 ~ mid of 2016) and recently as a professor up to date. He is supervising & teaching undergraduate & postgraduate students in Minia (1998 ~2012), Fayoum ( 2013~2104) & recently Damanhour Universities Egypt. He is a member of Egyptian Dental Association (EDA). He published many research articles in several international Journals & EDA Journal. He works as a reviewer for some scientific international Journals & also as an editorial board member for other scientific international Journals. Also, He presented researches in several international conferences and lectures in Egyptian Ministry of health and dental syndicate. His Doctor's Degree focused on use of bioabsorbable membranes, bone grafts & subepithelial connective tissue grafts in guided periodontal tissue regeneration (GTR). His Master's degree focused on Effect of CO2 Laser on Periodontally Involved root Surfaces. His researches including many scientific topics such as: GTR in aggressive & chronic periodontitis, Erosive-ulcerative lesions of lower lip with malignant potential, erosive ulcerative lesions of oral lichen planus, local delivery approach in type 2 diabetes mellitus & severe periodontitis, periodontal cell culture following CO2 and Er:YAG Laser conditioning, dentin hypersensitivity & mineral content using CO2 and Er:YAG Laser irradiations, enamel matrix proteins & dentin collagen as root surface biomodifiers, using Platelet derived growth factor-BB (PDGF-BB), EDTA gel or combination, or Er:YAG laser combined with PDGF-BB on cultured fibroblast cells; as well as usage of a new local delivery approach as adjunctive to non-surgical periodontal therapy..

Abstract: In our expertise in the area of specialty of periodontology, significant number of cases have been noticed to be referred for periodontist unfortunately after missing important steps in their treatment plan. This affects and reflects on worsening of the overall prognosis. Furthermore, some of these cases are even referred as hopeless with a complete poor prognosis, despite they have made many recall visits for multiple previous years for restorative and/or prosthetic purposes within the clinics of general dental practioners. So, what can periodontist do for treating such patients?. In fact, time factor and/or timing process is an essential part in referring patient in order the periodontist can do a thorough treatment plan and get the most successful results. Thus, reaching an excellent prognosis and achieving a good treatment as well as maintenance and longevity of the involved teeth and quadrants can be achieved by both earlier diagnosis and accurate patient's refer in the suitable time. -On the other hand, the presentation will cover an overview on some of the needed surgical procedures in the field of periodontal plastic surgery.

Jumana Sabbarini
Title: Esthetic restorations in PediatricDentistry..A new era…

Biography: Will be Updated Soon...

Abstract: A variety of esthetic restorative materials are available for restoring primary incisors and molars. Intracoronal restorations of primary teeth may utilize resin composites, glass ionomer cements, resin-modified ionomers, or polyacid-modified resins. Each has distinct advantages and disadvantages and the clinical conditions of placement may be a strong determining factor as to which material is utilized. Full coronal restoration of primary teeth may be indicated for a number of reasons. Crowns available for restoration of primary teeth include those that are directly bonded onto the tooth , which generally are a resin material, and those crowns that are luted onto the tooth and are some type of stainless steel crown. NuSmile Pediatric Crowns introduces Signature Crowns that are made of stainless steel, but they feature a natural-looking, tooth-colored coating for a more esthetic appearance. Recently, NuSmile ZR,Cheng Crowns,Kinder crowns and Flex Crowns( Pediatric Zirconia Crown)– the pediatric crowns that look like the real thing and is even better since its also stronger than natural teeth. Many options exist to repair carious primary teeth, but there is insufficient controlled, clinical data to suggest that one type of restoration is superior to another. This does not discount the fact that dentists have been using many of these crowns for years with much success. Operator preferences, esthetic demands by parents, the child’s behavior, and moisture and hemorrhage control are all variables which affect the decision and ultimate outcome of whatever restorative treatment is chosen.

Noorul Amin
Dental Department Federal Government polyclinic Hospital Islamabad Pakistan.


Abstract: The objective of this case presentation is to provide an insight on the subject of Gingival Recession and to share the results of the surgical management of gingival recession (Millers class 3 defect in maxillary pre-molar area) .One of the most common esthetic concerns associated with the periodontal tissues is gingival recession. Gingival recession is the exposure of root surfaces due to apical migration of the gingival tissue margins; gingival margin migrates apical to the cement-enamel junction, Therefore this deformity should be treated at its earliest detection. Exposed root surfaces are more likely to develop root sensitivity and root caries. Among various procedures, laterally positioned pedicle graft (LPG) is widely used successfully to cover recession defects. The main advantages of the laterally positioned pedicle graft are that it is relatively easy and not time-consuming, it produces excellent esthetic results and no second surgical site is involved for donor harvesting. The Present case report is about the successful surgical management of a patient with gingival recession i.e., Miller’s class III defect using laterally positioned pedicle graft.

Ludmila Gavriliuc
Nicolae Testemitanu State University of Medicine and Pharmacy, Moldova
Title: Interrelation between biochemical and clinical indices in children with gingivitis during treatment by complex antihomotoxic therapy

Biography: Ludmila Gavriliuc is Professor of Biochemistry and Clinical Biochemistry Department of Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Moldova. She graduated from the State Medical University, Medico-Biological Department, Speciality - Biochemistry, Moscow, Russia, and completed PhD (1978) and MD (1997) at the State Medical University, Moscow, Russia. She had the Scholarships in Russia, Italy, USA (01-08.2013, Fulbright Program U.S., Feist-Weiller Cancer Center, LSU HSC, LA). She is author of 107 scientific and methodic peer-reviewed manuscripts and 6 books. Participation in Conferences: USA, GB, Spain, Romania, Russia. Areas of the scientific interests are clinical-diagnostics, oncology, hematology, dentistry, antioxidant therapy.

Abstract: Introduction.The oral microbiota is responsible for gingivitis, which is characterized by an increase in the number and variety of inflammatory cells in the gindiva. Two important and interrelated factors are involved in the pathophysiological progression of gingivitis: the activation of oxygen radicals and their related metabolites. Increased production of oxygen radicals may contribute to oxidative stress. Inflammation is an activating factor of peroxide oxidation of lipids (POL) in periodontal tissues and disturbances of metabolism. Search of the newest and most effective drugs for treatment of gingivitis at the early stage of the disease and preventive therapeutic methods for inhibition progression to chronic forms of the disease has special value in modern dental practice. The antihomotoxic preparations, which may be recommended for solving this problem, are Traumeel S, Coenzyme compositum and Lymphomyosot. Usage of these antihomotoxic preparations based on their composition, properties, mechanism of action and possibility to use for oral application. Saliva as a biological liquid of the human organism may be a reflection of the metabolic state. Purpose of this investigation was a comparative examination of six salivary parameters and three clinical indices in the children with gingivitis during treatment by traditional methods and using complex therapy, including the antihomotoxic preparations. Material and methods. The 36 children (12 years) with gingivitis were treated traditionally (“Metrogyl-denta gel”, India) and with complex antitoxic therapy (Traumeel S ointment, Coenzyme compositum and Lymphomyosot, “Heel” GmbH, DE) during 7 days, and 25 healthy children (12 years) were the control group. The clinical effects were estimated with help of Green Vermilion, PMA indices and Pisarev-Shiller test. Saliva (mouth liquid) was collected in the morning and centrifuged at 600 g for 15 min. After centrifugation in saliva were determined with Spectrophotometry methods (DiaSysInt) the activities of glutathione reductase (GR), glutathione S-transferase (GST), and contents of reduced glutathione (RG), thiocyanate (SCN), proline and protein. Results. The first examination of the saliva in children with gingivitis showed the elevation activity of GST, content of protein, proline and low levels of RG (86,3%), GR (72,8%) and SCN (63,9%). Correlation Spirmean analysis indicated an imbalance between activities of GR and GST in the patients. Correlation analysis between the salivary biochemical parameters and clinical characteristics (indices) indicated the positive interrelation between RG and PMA before treatment (r=+0,758; p<0.01) and after end of both therapeutic courses. A strong positive correlation between PMA and SCN was indicated after complex therapy only (r=+0,864; p<0.01). Between PMA and proline before treatment an imbalance indicated, and after both therapeutic courses was found strong positive correlation. Conclusion. Traditional therapy increased activity of GST in comparison of complex treatment. Complex therapy restored imbalance of the antioxidant defense and was more effective that the traditional therapy alone in the children with gingivitis. This fact was confirmed by the dynamics of salivary biochemical and clinical indices, the more effective improvement of the patient’s health status, and the reduction of inflammation period and treatment course duration. Key words: gingivitis, glutathione, glutathione S-transferase, PMA, proline, SCN

Sharan sargod
Yenepoya University, Deralkatte, Mangalore
Title: Indirect pulp therapy –New insights

Biography: Prof. Dr. Sharan Sargod, earned his master’s degree( MDS) from RGHUS in 2002. Since then he is actively involved in teaching and research at Yenepoya University Mangalore India and has many publications in various national and international journals to his credit. He is also the director of Denture Clinics PVT. Ltd and. a consultant paediatric dentist to various clinics in and around Mangalore with special interest in the field of dental traumatology and preventive dentistry. He is the first recipient of the "Young Paedodontist award" by the Indian Society of Pedodontics & Preventive Dentistry and has been a guest speaker at various national conferences and meetings.

Abstract: Endodontic treatment principles originally evolved on the basis of trial and errors and only in recent decades have scientific methods been adopted to support clinical strategies. Yet relevant information on the disease process, their diagnosis and efficient treatment protocols are scares in the endodontic literature ,therefore many difference of opinions still prevail in the field of vital pulp therapy. Controversies still remain among practitioners including pediatric dentists as to which treatment modalities are most predictable in contemporary practice of pulp therapy. Many clinicians still remain divided as to whether indirect pulp therapy is a viable treatment procedure in primary and young permanent teeth. This lecture highlights some of the evidence based best practices related to management of deep carious lesions and vital pulp therapy in recent years.

Fred S Ferguson
Stony Brook University, United States
Title: Oral health provides the path to improved health and reduced cost

Biography: Dr Ferguson is a distinguished teaching professor (pediatric dentistry), Department of Orthodontics and Pediatric Dentistry School of Dental Medicine and an associate professor Department of Pediatrics, University Hospital, Stony Brook University. He has presented extensively to professional and community groups, developed educational and service programs to communities and has presented to healthcare industry. Dr. Ferguson is president and founder of About Smiles Inc. and ABOUTSMILESWORLD LTD., focused on integrating oral health into primary care with the goal to improving collaboration and reducing healthcare cost.

Abstract: The Grantmakers in Health (2012) publication, Returning the Mouth to the Body: Integrating Oral Health and Primary Care, makes logical sense. The focus of this idea is to provide information about a patient’s oral health to medical providers, giving them a better opportunity of identifying disease early and reduce cost in a patient-centered model of care. In addition, many aspects of primary care are failing, which has increased the burden on chronic care. Primary Care could mitigate these failures by capturing pertinent information about how consumers manage their oral health over time. The behaviors, habits, and lifestyle choices that impact oral health are also risk factors for common chronic diseases such as diabetes, cardiac problems, and obesity. This oral health information could be used by Primary Care as an early alert signal of issues with long-term health and quality of life. These insights indicate that a patient’s oral health profile could significantly benefit primary and chronic care management. I call this oral health profile, comprised of the patient’s information confirmed by the outcomes of their dental examination, Smart Data. Smart data can provide benefits to improve population health and reduce disparities and inequities for consumers and improve collaboration across healthcare. As a consumer behaviors, habits and lifestyle choices are very significant to their health journey, a logical first step is to enable consumers to become competent health managers. Integration of oral health data in healthcare would improve the relationship of consumers, providers, payers and policy and confirm the value of oral health to systemic health and beyond.

Noha Ayman Ghallab
Cairo University, Egypt
Title: Oral fluid biomarkers in the diagnosis and prognosis of periodontal diseases: Evidence-based practice and future directions

Biography: Prof.Noha Ghallab graduated from faculty of Dentistry, Cairo University (Egypt), as the first of her class in 1997, in 2002 she finished her MSc degree and received her PhD at 2005 in Periodontology and Oral medicine.Since 2017 she is holding the post of Professor of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University. Dr Ghallab published 13 articles in peer-reviewed international journals with 82 citations and an h-index of 5 & is a peer-reviewer in international journals. She participated in national and international conferences e.g. “Europerio8” London 2015 &Eurocongress on dental & oral health, Rome 2016.

Abstract: The holy grail of biomarker research in periodontology is to develop a “high impact diagnostics” which have a significant impact on clinical decision-making, patient outcomes and healthcare providers.In the field of periodontal diagnostics, oral fluid-based biomarkers have been studied mainly in the GCF and saliva.A literature search was performed using the Cochrane library and PubMed databases from 2000 to 19 January 2017, with the following search strategy: (“gingivitis” OR ‘‘periodontitis’’ OR ‘‘periodontal disease’’) AND (‘‘biomarkers’’ OR ‘‘markers”) AND (‘‘saliva’’ OR “salivary” OR ‘‘gingival crevicular fluid’’). Potential biomarkers of periodontal disease activity would either be involved in disease pathogenesis or released because of tissue damage during disease progression. The major attraction of GCF as a source of biologic markers is the site-specific nature of the sample. Up till now, there are more than 90 different components in the GCF that have been investigated as diagnostic and prognostic markers of periodontal disease progression involving; inflammatory mediators, markers of oxidative stress, host-derived enzymes, tissue-breakdown products and mediators of bone homeostasis. Various biomarkers in saliva have been proposed which reveal a promising outlook for saliva as a key diagnostic medium for periodontal disease. Recent systematic reviews with high value of evidence have shown that potential salivary biomarkers can provide important complimentary diagnostic information and can be used as tests for screening diagnosis, prognosis and predicting periodontal disease progression.Future developments in proteomic analysis and personalized medicine will pave the way allowing novel diagnostictools. Still, the application into the field of dentistry will depend on how practitioners will apply this into their daily clinical practice.

Saint Joseph University Campus des sciences médicales Lebanon
Title: Uncooperative patient : dental treatment under conscious sedation or general anesthesia

Biography: Chairperson – Professor . Department of Pediatric Dentistry Saint- Joseph University,Beirut- Lebanon. Pr Abou Chedid graduated from Saint-Joseph University, School of Dentistry (FMD) in Beirut, Lebanon. He holds a post-graduate degree (CES) in Paediatric Dentistry from Garancière University – Paris VII. He hold a DEA and PHD from Saint-Joseph University, School of Dentistry (FMD) in Beirut, Lebanon He is currently a Professor in the Department of Paediatric Dentistry at Saint Joseph University where he has just been appointed as a Chairman of the same department. Pr Abou Chedid is the former President of the Lebanese Society of Paediatric Dentistry and of the Arab Association of Paediatric Dentistry. Pr Abou Chedid has lectured nationaly and internationaly (Lebanon, France, Syria, Egypt, Morroco, Tunisia, Qatar, Dubai and Belgium). He has also published a number of articles and is involved in a number of ongoing studies. Pr Abou Chedid has a private practice in Lebanon, limited to Pediatric dentistry.

Abstract: Inhalation sedation utilizing nitrous oxide - oxygen has been a primary technique in the management of anxiety and dental fears. It is usually the technique of choice for paediatric dental conscious sedation, children with special needs and for adults.She can reduce the need for general anesthesia. Conscious sedation is a technique in which the use of a drug or drugs produces a state of depression of the central nervous system enabling treatment to be carried out, during which patients are able to respond purposefully to verbal commands or light tactile stimulation. But careful attention also needs to be given to selecting appropriate dental patients for sedation. The technique has an extremely high success rate coupled with a very low rate of adverse effects and complications.The indications, contra indication and operative protocol will be presented during this communication.

King George Medical University, Lucknow, India
Title: Vitamin D for Periodontium : A New Warrior

Biography: will update soon..

Abstract: Periodontal disease is the leading cause of tooth loss in adults, so its prevention is important because poor oral health and tooth loss may impede consumption of a nutritious diet which reduces quality of life and is associated with systemic diseases such as type 2 diabetes and cardiovascular disease. Chronic periodontitis is a disease of inflammation thought to result from oral bacterial infection. The body’s immune response to infection can lead to periodontal tissue destruction and characterized by alveolar bone loss induced by the host immune response to bacterial insult. It is hypothesized that vitamin D status could modify risk for periodontal disease by preventing alveolar bone loss or by mediation of the host’s immune response to infection and resultant inflammatory response. The main function of vitamin D is to support calcium homeostasis, but it also plays an important role in immunity, the cardiovascular system, diabetes, cancer, and chronic illnesses. The primary sources of vitamin D are dietary intake and sunlight exposure in the form of vitamin D2 and D3, which are metabolized to 25-hydroxyvitamin D [25(OH)D] in the liver. Further metabolism in the kidneys produces the active form of vitamin D, 1,25-dihydroxyvitamin D. It is well known that the active vitamin D is needed for calcium homeostasis in the blood which plays a crucial role in bone maintenance and immunity and there is biologic rationale to suspect that a vitamin D deficiency could negatively affect the periodontium. Vitamin D deficiency is highly prevalent, with an estimated 1 billion people affected worldwide. However it is difficult to estimate the prevalence due to a lack of consensus about the definition, and recent information suggests that this may be overestimated. In addition, mean serum 25(OH)D levels appear to be declining over the past several decades, due to changes in Body Mass Index, dietary intake, and sun exposure.

ITS Dental College, Muradnagar, India
Title: Comparative evaluation of five different approaches for the treatmentof hyperpigmentation- a clinical and histological study

Biography: Will update soon..

Abstract: Background: Gingival melanin depigmentation techniques are frequently associated with reoccurrence of pigmentation, which begins with migration of melanocytes from the adjoining free gingiva. The degree and pace of reoccurrence differs according to the treatment modalities employed and period of follow-up. In the present study, the effectiveness of a various approaches were tested and compared while treating gingival hyperpigmentation (GH). Materials and Methods: Fifty patients diagnosed of GH were selected for the study. Patients were equally but randomly divided into five different groups: i) Group 1- Surgical Blade; ii) Group 2-Bur abrasion; iii) Group 3- Electrocutery ; iv) Group 4- GaAlA diode laser at wavelength of 980 nm; v) Group 5- Cryosurgery. Standardized clinical parameters included the Visual Analogue Scale (VAS) score for patient preference perception, Wound healing index(WHI),change in Dummett oral pigmentation index (DOPI) and change in area of pigmentation from baseline to 6 months postoperatively. Readings were recorded and analyzed at baseline and at 6 month. Results: At the 6-month postoperative visit, diode laser-treated sites showed no clinical and histologic repigmentation. Comparison of wound healing score and pain score (VAS)using one way ANOVA and Kruskal Wallis test, respectively, were statistically significant for laser depigmentation (P = 0.001). P values for comparison of microscopic evaluation and change in DOPI were 0.001, which were statistically significant. Conclusion: Within the limits of this study, it is safe to conclude that the depigmentation treatment modality using Diode laser proved to be most effective in terms of wound healing and pain perception as compared to scalpel, bur, electrosurgery and cryosurgery method.

Chaudhry Anshul
Government Dental College Haryana, India

Biography: Will update soon..

Abstract: Dental and dental personnel’s are constantly exposed to a number of specific occupational hazards. This article analyze the potential hazards and various risks involved in persons exposed to prosthodontic practice mainly prosthodontist and the laboratory technicians. These risks include exposure to chemical, physical hazards, infectious environment, psychosocial hazards and various others. Personnel’s working in the prosthodontic clinic should be aware of the specific risk factors and take necessary measures to prevent and overcome these hazards.

Head Department of Public Health Dentistry University, Lahore, Pakistan
Title: Relationship between Periodontal disease and Systemic inflammation in Coronary Heart Disease patients with or without smoking and/or diabetes

Biography: Will update soon..

Abstract: Background: Scientific research provides evidence on association of periodontal disease, coronary heart disease (CHD) and systemic inflammation. Smoking and diabetes, common risk factors for both periodontal and coronary heart disease, play a role in systemic inflammation. This study tried to observe association of periodontal disease, inflammatory markers and CHD in smoker-diabetic males. Methodology: A cross-sectionalstudy of eligible CHD males with periodontitis was conducted at Punjab institute of cardiology Lahore Pakistan in April 2016. Study subjects were dividedinto four groups: smoker-diabetic (group A), smoker non-diabetic (group B), non-smoker-diabetic (group C) and non-smoker non-diabetic (group D) for a comparison in status of periodontal and inflammatory parameters. Bleeding on probing, periodontal pocket depth and clinical attachment loss were noted as measures of periodontal status. Serum levels of CRP, WBC and Fibrinogen were measured. Differences of periodontal and inflammatory parameters between groups A, B, C and D were analyzed using K-test of proportions and one-way ANOVA. Results: Fifty two CHD males were observed. There was no statistically significant difference between groups A, B, C and D with respect to demographic parameters of age, socioeconomic status and BMI. Levels of BOP, PPD, CAL, CRP, WBCs and fibrinogen were comparatively higher in group A.Mean levels of BOP, PPD, CAL and WBC were significant (p≤0.050) however levels of CRP and fibrinogen were insignificant between groups. Thirty eight percent subjects with ≥4mmPPD and ≥3mm CAL at >30% of sites showed CRP levels of > 3mg/L. Subjects with CRP levels of > 3mg/L were significantly higher in group A (p=0.015). Conclusion: This study showed thatperiodontal disease is significantly associated with CHD risk factors of systemic inflammation. Levels of periodontal and inflammatory parameters were higher in smoker-diabetic patients.

Dental and Oral Health Congress 2017 | by: Scientific Future Group